What is Garcinia Cambogia?
What is Garcinia Cambogia?
In 1969, a team of biochemists from Brandeis University led by John Lowenstein, who explored the mechanism of production of cellular energy (Krebs cycle, for connoisseurs) interested in the substance found at the end of the last century, that Indian scientists have isolated several local plants. The hydroxycitric acid (HCA) is a chemical cousin of citric acid present in citrus fruits. Our biochemical realized that blocking the activity of an enzyme that is responsible for the conversion of sugars into fat reserves of food for the body. Loewenstein has presented his work at the Swiss pharmaceutical giant Roche. Seduced, the laboratory must perform more work for the implementation of HCA in the treatment of overweight.
One of the best sources of HCA is a plant - Garcinia Cambogia – that grows in South India and produces a fruit flavor for the preparation of curry.
How does it work?
HCA blocks the activity of the ATP citrate lyase enzyme responsible for the conversion of by-products of dietary carbohydrates into fat. HCA and increases the production and storage of glycogen – the fuel used to quickly store in the muscles and liver. HCA also reduces appetite.
Scientific and clinical
Studies in rats have demonstrated the efficacy of Garcinia Cambogia and HCA extract: animals eat less and lose weight. In one study, the administration of HCA led to a decrease in appetite that lasts for more than seven weeks. In another study with rats, rats ate 10% less food than untreated rats. In humans, there are studies. 1994 A controlled study of 50 obese patients found two months after a weight loss of 5 pounds on average in the group receiving 500 mg of extract (with 100 mcg of chromium picolinate). The group that took a placebo lost weight only 2 pounds. All participants followed a low-fat diet. However, the same study in 1999 failed to demonstrate the efficacy of Garcinia Cambogia extract for weight loss in 66 obese people.
For more information, you can take the information here: Garcinia Cambogia
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